Professor Alexander Green
College Lecturer in Medicine (Neuroscience)
Professor of Neurosurgery & Consultant Neurosurgeon
Alex Green graduated from University College London in 1997 with a medical degree (MB BS) and BSc (hons) in Neuroscience. After junior doctor posts around the UK he joined the Neurosurgical Specialty training programme in Oxford and became a consultant in 2009 at the Oxford University Hospitals NHS Foundation Trust. He holds appointments in both the NHS and University of Oxford where he is Professor of Neurosurgery. His research relates to Neuromodulation and in particular Deep Brain Stimulation, Dorsal Root Ganglion Stimulation. He has an interest in the treatment of chronic pain and control of the autonomic nervous system. More recently he has been exploring non-invasive brain stimulation using transcranial focused ultrasound (TUS). He runs a number of medical device trials and develops devices in collaboration with the department of Engineering. He is also an academic director of the Surgical Interventions Trials Unit (SITU).
Undergraduate Teaching
Alex teaches second year undergraduate students at Hertford, concentrating on Neuroscience. He also supervises FHS student projects in the third year. He teaches clinical medical students and is an examiner for year four OSCEs and finals.
Graduate
Alex teaches on a number of MSc courses including Surgical Science and Practice and Neuroscience. He is course director for Abbott’s Neuromodulation Fellowship (a three-part European course that teaches Doctors how to do spinal cord stimulation). He also teaches on a Neuromodulation MSc based in London. He is currently a primary supervisor for 4 D Phil students.
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Research interests
There are two main parts to Alex’s research programme; medical device trials and basic research looking at autonomic function. He set up and is chief investigator on the EPIONE trial; a randomized controlled trial using a novel Deep Brain Stimulation device for chronic post-stroke pain. The aim is to show efficacy at the same time as understanding mechanisms and developing better therapies e.g. closed loop stimulation based on local field potential biomarkers of pain and chronotherapy (varying stimulation at different times of day). He is setting up a pilot study stimulating the brainstem in minimally conscious state with similar device development. More recently he has been investigating transcranial focused ultrasound as a method to predict response to DBS and to look for individualized targeting for DBS. This has so far been applied to movement disorders and pain. His basic science research focusses on the role of the dorsal root ganglion and whether this can be stimulated in cardiovascular disorders such as arrythmias and hypertension. He is a founding member of an Oxford University start up called Amber that manufactures neuromodulation devices.
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Related websites
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Publications
For publications list, please see Alex’s NDS website.