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Home / Our people / Professor Petros Ligoxygakis

Professor Petros Ligoxygakis

Tutorial Fellow in Biochemistry & Student Conduct Officer

Professor of Innate Immunology

petros.ligoxygakis@bioch.ox.ac.uk

Petros holds a BSc (Hons) degree in Biology from the University of Athens, Greece. He then moved to the south of the country for his PhD, at the Institute of Molecular Biology and Biotechnology in Heraklion, Crete, an Institute founded by Fotis Kafatos. On completion of his PhD, he obtained a Long-Term Postdoctoral Fellowship from the European Molecular Biology Organisation (EMBO) to work in the lab of Jules Hoffmann at the CNRS in Strasbourg where he trained in the study of innate immunity in insects. This was followed by a University Lectureship in Genetics at the Department of Biochemistry and a non-Tutorial Fellowship at St Cross College. In 2016 he was awarded the title of Professor of Innate Immunology and in 2018 he transferred to a Tutorial Fellowship at Hertford. He is a Fellow of the Royal Entomological Society.

Undergraduate teaching

Petros is responsible for the immunology and some of the developmental biology tutorial teaching for Hertford biochemists. He also teaches molecular biology and genetics. Within the Department of Biochemistry, Petros gives third year lectures on immunology and developmental biology and he is also involved in teaching the undergraduate laboratory course of the first year.

Graduate teaching

Petros has an active research group within the Department of Biochemistry, and supervises a number of postdoctoral fellows, DPhil students and fourth year (“Part II”) students on the MBiochem course.

  • Research interests

    Petros’s research interests include innate immunity and its role in infection, host-pathogen interaction and ageing using the fruit fly Drosophila as a model. Recently, his research developed in studying the immune system of insect vectors that transfer deadly infectious diseases to humans. Further details of Petros’s research can be found at www.bioch.ox.ac.uk/research/ligoxygakis

  • Related websites

    https://www.bioch.ox.ac.uk/research/ligoxygakis

  • Publications

    Recent (2020-2019) publications/preprints

    • Sloan MA, Sadlova J, Lestinova T, Sanders MJ, Cotton JA, Volf P, Ligoxygakis P (2020) The Phlebotomus papatasi transcriptomic response to trypanosomatid-contaminated blood is robust but non-specific. bioRxiv doi: https://doi.org/10.1101/867382
    • Wang L, Sloan MA, Ligoxygakis P (2019) Intestinal NF-ÎşB and STAT signalling is important for uptake and clearance in a Drosophila-Herpetomonas interaction model. PLoS Genetics 15(3): e1007931
    • Sloan MA, Brooks K, Otto TD, Sanders MJ, Cotton JA, Ligoxygakis P (2019) Transcriptional and genomic parallels between the monoxenous parasite Herpetomonas muscarum and Leishmania. PLoS Genetics 15(11): e1008452.
    • Vaz F, Kounatidis I, Covas G, Parton RM, Harkiolaki M, Davis I, Filipe SR, Ligoxygakis P (2019), Accessibility to Peptidoglycan Is Important for the Recognition of Gram-Positive Bacteria in Drosophila. Cell Reports 27, 2480-2492.

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